J Curr Surg

Journal of Current Surgery, ISSN 1927-1298 print, 1927-1301 online, Open Access

Article copyright, the authors; Journal compilation copyright, J Curr Surg and Elmer Press Inc

Journal website http://www.currentsurgery.org

Original Article

Volume 7, Number 4, December 2017, pages 53-57

Effect of Duration of Surgery on Liver Enzymes After Cholecystectomy: Safety or Duration

Tables

**Table 1.** Gender Distribution of Patients
Group A (10 mm Hg) (N = 100)		Group B (14 mm Hg) (N = 100)		Group C (OC) (N = 100)
Males	Females	Males	Females	Males	Females
15 (15%)	75 (75%)	22 (22%)	78 (78%)	20 (20%)	80 (80%)

**Table 2.** Duration of Surgery in Three Groups Undergoing Laparoscopic Cholecystectomy Done in a Single Unit
Duration in minutes	Group A	Percentage	Group B	Percent	Group C	Percent
20 - 30	58	58	70	71	2	2
31 - 40	12	12	10	10	4	4
41 - 50	14	14	10	10	30	30
51 - 60	6	6	6	6	24	24
61 - 70	6	6	6	6	30	30
71 - 90	4	4	8	8	10	10

**Table 3.** Effects on LFT in Low and High Pressure Group With Duration Less Than One Hour
Parameters	Group A before surgery	Group A after surgery	Group B before surgery	Group B after surgery	Group C (OC) before surgery	Group C (OC) after surgery
Bilirubin	0.6162 ± 0.20	0.60 ± 0.22	1.8 ± 0.22	1.9 ± 0.01	0.51 ± 0.1	0.54 ± 0.2
AST	68.15 ± 10.50	61.58 ± 11.2	66.4 ± 11.3	69 ± 0.35	26.0 ± 4.7	28.2 ± 4.8
ALT	98.50 ± 13.78	99.65 ± 15.79	60.8 ± 10.54	72 ± 0.57	24.5 ± 4.7	27.7 ± 4.9
ALP	128.79 ± 34.66	132 ± 20.23	98.40 ± 36	88.39 ± 33.35	59.8 ± 13.6	61 ± 12.04

**Table 4.** Effects on LFTS in Low and High Pressure Group With Duration More Than One Hour
Parameters	Group A before surgery	Group A after surgery	Group B before surgery	Group B after surgery	Group C (OC) before surgery	Group C (OC) after surgery
Bilirubin	0.57 ± 0.35	0.99 ± 1.46	0.383 ± 0.34	0.623 ± 0.26	0.61 ± 0.1	0.61 ± 0.2
AST	68.15 ± 24	78.45 ± 27	38.51 ± 16.23	48.13 ± 0.56	29.0 ± 4.7	26.2 ± 4.8
ALT	98.50 ± 24.57	124 ± 0.57	49.33 ± 0.36	65.96 ± 78	29.5 ± 4.7	32.7 ± 4.9
ALP	110.68 ± 18.89	128.79 ± 24.7	98.40 ± 15	110 ± 2.8	59.8 ± 13.6	61 ± 12.04

**Table 5.** Changes in LFT in Patients Who Underwent Open Cholecystectomy After 48 h of Procedure
Parameter	24 h before OC (pre-operative mean)	48 h after OC (postoperative mean)	P value
Serum bilirubin	0.51 ± 0.1	0.51 ± 0.2	NS
AST (IU/L)	26.0 ± 4.7	26.2 ± 4.8	NS
ALT (IU/L)	24.5 ± 4.7	24.7 ± 4.9	NS
ALP (IU/L)	59.8 ± 13.6	61 ± 12.04	NS