Impact of Gastroesophageal Reflux Disease on Patients Undergoing Lung Transplantation for COVID-19: A Single Institution Retrospective Study

Christopher Kim, Daniel Bushyhead, Edward Chan, Howard Huang, Ray Chihara, Ahmad Goodarzi, Simon Yau, Jihad Youssef, Thomas Macgillivray, Erik Suarez, Philip Chou, Gulchin Ergun


Background: Patients with coronavirus disease 2019 (COVID-19)-associated respiratory failure undergoing lung transplantation is an emerging subset of transplant patients in which gastroesophageal reflux disease (GERD) pre- or post-transplant is not well characterized.

Methods: We retrospectively evaluated patients undergoing lung transplant for COVID-19, with attention to pre- and post-operative physiological testing for GERD.

Results: Seventeen patients were identified who had undergone lung transplant for COVID-19. No patient underwent pre-transplant GERD testing. Post-transplant, 70.5% (12/17) patients reported reflux symptoms confirmed with additional testing. Three patients underwent anti-reflux surgery (ARS) based on results of testing, and none had complications or symptom-based recurrence of reflux.

Conclusion: Our study depicts a unique cohort of patients who were unable to undergo pre-transplant testing for GERD in the setting of a global pandemic, and who were routinely assessed and managed post-transplant.

J Curr Surg. 2023;000(000):000-000


Gastroesophageal reflux disease; Lung transplant; COVID-19 infection

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