Necrotizing Breast Infection: A Rare Entity and a Management Challenge

Hassan Masoudpour, Jessica Wassef, Alain Cagaanan, Jausheng Tzeng, Jenna Gillen, Rachelle Leong


Necrotizing infection of the breast associated with pre-existing malignancy, is a rarely encountered clinical scenario. This rarity, coupled with its potential life-threatening consequences and the complexities introduced by treatments like neoadjuvant chemotherapy and immunotherapy, highlights the need for timely and accurate intervention. We present the case of a 51-year-old female who was diagnosed with inflammatory triple-negative breast cancer. After undergoing neoadjuvant chemotherapy and immunotherapy, she developed a necrotizing infection of the breast. This required emergency surgical debridement and palliative mastectomy to remove the source of infection. This case underscores the crucial role of surgical management in such complex scenarios, particularly in the context of sepsis.

J Curr Surg. 2024;14(1):11-16


Necrotizing infection; Triple-negative breast cancer; Inflammatory breast cancer; Surgical debridement; Sepsis; Palliative mastectomy

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